Preliminary investigation into the effects of SlimBiome® on food cravings and responsiveness to the food environment in healthy overweight and obese women following standard nutritional advice

Source: Proceedings of the Nutrition Society (2018), 77 (OCE4), E229.

Aim: The aim of this study was to investigate the effect of SlimBiome®, a commercially available product, on food cravings and the responsiveness of individuals to the food environment, which are characteristics associated with hunger(2,3), in overweight and obese women following standard nutritional advice. SlimBiome® contains fibre (glucomannan), prebiotics and chromium, which have been shown to increase satiety and reduce energy intake, hunger and fat cravings in overweight and obese adults.

Methods: A double-blind, randomised, placebo-controlled study was conducted in 20 overweight and obese women over a 4-week period. Inclusion criteria included women aged 18–65 years, with a body mass index between 25–35 kg/m2, no significant health problems, and no history of dieting within the month prior to starting the study. Participants attended three study visits at week 0, week 1 and week 4. At week 0 they were randomly assigned to receive the test drink or placebo and were instructed to consume the drink three times a day for 4 weeks. At each visit, participants rated subjective sensations of appetite before and after consuming the test drink or placebo and completed the Control of Eating Questionnaire (CofEQ) and the Power of Food Scale (POF).Results: For the CofEQ, ratings in response to ‘How hungry have you felt?’ at week 4 were significantly lower in the treatment group compared to the placebo group (P = 0.034). For the POF Scale, scores decreased significantly after the 4-week intervention period in both the placebo group (P = 0.035) and the treatment group (P = 0.007).


In conclusion, subjective feelings of hunger measured by the CofEQ were significantly reduced in women who consumed SlimBiome® compared to placebo. Although cravings appeared to subside more in women consuming SlimBiome®, no significant difference was seen compared to placebo. This may be due to both groups becoming less responsive to the food environment, a characteristic shown to predict strength of and ability to resist cravings.